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Article

Molecular characterization of TP53 gene in human populations exposed to low-dose ionizing radiation.

BioMed research international - 1 Jan 2013

Brasil-Costa Igor, Alencar Dayse O, Raiol-Moraes Milene, Pessoa Igor A, Brito Alexandre W M, Jati Schneyder R, Santos Sidney E B, Burbano Rommel M R, Ribeiro-dos-Santos Andrea K C

Abstract excerpt

Ionizing radiation, such as that emitted by uranium, may cause mutations and consequently lead to neoplasia in human cells. The TP53 gene acts to maintain genomic integrity and constitutes an important biomarker of susceptibility. The present study investigated the main alterations observed in exons 4, 5, 6, 7, and 8 of the TP53 gene and adjacent introns in Amazonian populations exposed to radioactivity. Samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23586029
DOI: 10.1155/2013/303486
PMCID: PMC3613089

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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