Article
Evaluation of the polymorphisms in the exons 2 to 4 of the TP53 in cervical carcinoma patients from a Brazilian population.
Cellular and molecular biology (Noisy-le-Grand, France) - 1 Jun 2008
Fernandes T A A M, Lima G L F, De Souza F C G, Fernandes J V, Meissner R V
Abstract excerpt
The majority of TP53 polymorphisms and cervical cancer association studies have only analyzed codon 72 polymorphism. Eight polymorphisms were reported in the region encompassing exon 2 to 4 of TP53 that codify the aminoterminal p53 region containing domains involved in the transcription transactivation and apoptosis induction. We investigated if the polymorphisms present in this region were associated with...
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