An intronic variant in the TP53 gene in a Brazilian woman with breast cancer.

Abstract excerpt

We screened the TP53 gene for mutational status in 40 breast tumor cases by polymerase chain reaction, single-strand conformational polymorphism, and gene sequencing. Many mutations of this gene have been described in specific databases. In our study, a new T-->C point mutation was identified in intron 6 at position 13989 in a grade III medullary ductal carcinoma. Other variations in intron 6 have been described...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Brazil
• Share to Breast Neoplasms