Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation of the ghrelin signalling system in individuals with amphetamine dependence.

PloS one - 1 Jan 2013

Suchankova Petra, Jerlhag Elisabet, Jayaram-Lindström Nitya, Nilsson Staffan, Toren Kjell, Rosengren Annika, Engel Jörgen A, Franck Johan

Abstract excerpt

The development of amphetamine dependence largely depends on the effects of amphetamine in the brain reward systems. Ghrelin, an orexigenic peptide, activates the reward systems and is required for reward induced by alcohol, nicotine, cocaine and amphetamine in mice. Human genetic studies have shown that polymorphisms in the pre-proghrelin (GHRL) as well as GHS-R1A (GHSR) genes are associated with high alcohol...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amphetamine
Share to Amphetamine-Related Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Ghrelin

Share to Haplotypes

Share to Receptors, Ghrelin

Share to Signal Transduction

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 23579732
DOI: 10.1371/journal.pone.0061242
PMCID: PMC3620267

Genes

GHRL
GHSR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation of the ghrelin signalling system in individuals with amphetamine dependence.PMID 23579732Read ↗

Genetic variation of the growth hormone secretagogue receptor gene is associated with alcohol use disorders identification test scores and smoking.Semantic proximity Read ↗

Genetic variation of the ghrelin signaling system in females with severe alcohol dependence.Semantic proximity Read ↗

Association of pro-ghrelin and GHS-R1A gene polymorphisms and haplotypes with heavy alcohol use and body mass.Semantic proximity Read ↗

The Role of Ghrelin/GHS-R1A Signaling in Nonalcohol Drug Addictions.Semantic proximity Read ↗

A case control study investigating the methylation levels of GHRL and GHSR genes in alcohol use disorder.Semantic proximity Read ↗

Reward-related genes and personality traits in alcohol-dependent individuals: a pilot case control study.Semantic proximity Read ↗

OPRM1 gene variants modulate amphetamine-induced euphoria in humans.Semantic proximity Read ↗

The Leu72Met Polymorphism of the Prepro-ghrelin Gene is Associated With Alcohol Consumption and Subjective Responses to Alcohol: Preliminary Findings.Semantic proximity Read ↗

Genetic analysis of the mu-opioid receptor in alcohol-dependent individuals.Semantic proximity Read ↗

Ghrelin precursor gene polymorphism and methamphetamine dependence in the Korean population.Semantic proximity Read ↗

Reward-seeking behavior and addiction: cause or cog?Semantic proximity Read ↗

More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.