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Article

Reward-related genes and personality traits in alcohol-dependent individuals: a pilot case control study.

Neuropsychobiology - 1 Jan 2011

Landgren Sara, Berglund Kristina, Jerlhag Elisabet, Fahlke Claudia, Balldin Jan, Berggren Ulf, Zetterberg Henrik, Blennow Kaj, Engel Jörgen A

Abstract excerpt

Components of the brain reward system, i.e. the mesolimbic dopamine, laterodorsal cholinergic and ghrelin signaling systems, have been implicated in alcohol reward in preclinical studies. Genetic variants of these systems have previously been linked to alcohol dependence. Here, we genotyped 31 single nucleotide polymorphisms (SNPs): 1 SNP in the dopamine D₂ receptor (DRD2) gene, 20 SNPs in 5 different nicotinic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21606657
DOI: 10.1159/000324992

Genes

GHRL
GHSR
CHRNB3
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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