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Article

More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2010

Dlugos Andrea M, Hamidovic Ajna, Hodgkinson Colin A, Goldman David, Palmer Abraham A, de Wit Harriet

Abstract excerpt

Amphetamine is a stimulant drug that enhances attention and feelings of alertness. Amphetamine's effects are known to be modulated by endogenous cannabinoids, which are degraded by the enzyme fatty acid amide hydrolase (FAAH). In this study we investigated inter-individual differences in mood response to amphetamine in relation to four polymorphisms in the FAAH gene, including the FAAH missense variant rs324420C...

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Source

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Identifiers

PMID: 19890266
DOI: 10.1038/npp.2009.166
PMCID: PMC2945903

Genes

FAAH
TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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