Article
The association of single nucleotide polymorphisms in the calcitonin gene with primary osteoarthritis of the knee in Mexican mestizo population.
Rheumatology international - 1 Oct 2013
Magaña J J, Muñoz B, Borgonio-Cuadra V M, Razo-Estrada C, González-Huerta C, Cortés-González S, Albores A, Miranda-Duarte A
Abstract excerpt
Primary osteoarthritis (OA) is a multifactorial disorder with several genetics factors involved. Calcitonin (CT) has been suggested to possess chondroprotective effects and could play an important role in the pathogenesis of OA. The aim of this study was to investigate whether genetic variations in or adjacent to the CT gene may be associated with primary OA of the knee in Mexican mestizo population. We conducted...
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