Article
Association of PPARγ gene polymorphisms with osteoarthritis in a southeast Chinese population.
Journal of genetics - 1 Dec 2014
Zheru Ding, Peiliang Fu, Yuli Wu, Haishan Wu, Qirong Qian, Xiaohua Li, Hui Zhao, Bo Wang, Qiwei Fu
Abstract excerpt
Primary osteoarthritis (OA) is a leading cause of disability in developed countries. Currently no satisfactory treatment to stop disease progression exists. Recent studies suggest that activation of the transcription factor peroxisome proliferator-activated receptor gamma (PPARγ) is an interesting therapeutic target for this disease. PPARγ is a transcription factor important for adipogenesis and adipocyte...
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