Article
Can certain genotypes predispose to poor asthma control in children? A pharmacogenetic study of 9 candidate genes in children with difficult asthma.
PloS one - 1 Jan 2013
Almomani Basima, Hawwa Ahmed F, Millership Jeffrey S, Heaney Liam, Douglas Isabella, McElnay James C, Shields Michael D
Abstract excerpt
OBJECTIVE: We tested the hypothesis that patients with difficult asthma have an increased frequency of certain genotypes that predispose them to asthma exacerbations and poor asthma control. METHODS: A total of 180 Caucasian children with confirmed asthma diagnosis were selected from two phenotypic groups; difficult (n = 112) versus mild/moderate asthma (n = 68) groups. All patients were screened for 19...
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