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Article

Cyclooxygenase-1 gene polymorphisms in patients with different asthma phenotypes and atopy.

The European respiratory journal - 1 Aug 2005

Shi J, Misso N L A, Duffy D L, Bradley B, Beard R, Thompson P J, Kedda M-A

Abstract excerpt

Cyclooxygenase-1 (COX-1) regulates the biosynthesis of prostaglandins, which are important mediators in asthma. The possible association of COX-1 gene polymorphisms with asthma has not been investigated. The allele frequencies of 20 COX-1 polymorphisms were determined in a random Australian Caucasian population using MassARRAY technology. Informative and potentially functional promoter (c.8592C > T, c.1676C > T)...

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Identifiers

PMID: 16055872
DOI: 10.1183/09031936.05.00140104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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