Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans.

Biogerontology - 1 Apr 2013

Montesanto Alberto, Crocco Paolina, Tallaro Federica, Pisani Francesca, Mazzei Bruno, Mari Vincenzo, Corsonello Andrea, Lattanzio Fabrizia, Passarino Giuseppe, Rose Giuseppina

Abstract excerpt

Nitric oxide (NO) triggers multiple signal transduction pathways and contributes to the control of numerous cellular functions. Previous studies have shown in model organisms that the alteration of NO production has important effects on aging and lifespan. We studied in a large sample (763 subjects, age range 19-107 years) the variability of the three human genes (NOS1, -2, -3) coding for the three isoforms of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Activities of Daily Living
Share to Cognition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depression

Share to Geriatric Assessment

Share to Longevity

Share to Nitric Oxide Synthase Type I

Share to Nitric Oxide Synthase Type II

Share to Nitric Oxide Synthase Type III

Source

Identifiers

PMID: 23572278
DOI: 10.1007/s10522-013-9421-z

Genes

NOS1
NOS2
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans.PMID 23572278Read ↗

Genetic Factors of Nitric Oxide’s System in Psychoneurologic DisordersSemantic proximity Read ↗

Neuronal nitric oxide synthase (NOS1) and its adaptor, NOS1AP, as a genetic risk factors for psychiatric disorders.Semantic proximity Read ↗

Human Nitric Oxide Synthase-Its Functions, Polymorphisms, and Inhibitors in the Context of Inflammation, Diabetes and Cardiovascular Diseases.Semantic proximity Read ↗

Variants within the nitric oxide synthase 1 gene are associated with stroke susceptibility.Semantic proximity Read ↗

Endothelial nitric oxide synthase: From biochemistry and gene structure to clinical implications of NOS3 polymorphisms.Semantic proximity Read ↗

Genetic variation in NOS1AP is associated with sudden cardiac death: evidence from the Rotterdam Study.Semantic proximity Read ↗

Nitric oxide synthase (NOS) single nucleotide polymorphisms are associated with coronary heart disease and hypertension in the INTERGENE study.Semantic proximity Read ↗

Antioxidants and Quality of Aging: Further Evidences for a Major Role of TXNRD1 Gene Variability on Physical Performance at Old Age.Semantic proximity Read ↗

Clinically relevant endothelial nitric oxide synthase polymorphisms and their impact on drug response.Semantic proximity Read ↗

Association of a functional NOS1 promoter repeat with Alzheimer's disease in the VITA cohort.Semantic proximity Read ↗

Common NOS1AP variants are associated with a prolonged QTc interval in the Rotterdam Study.Semantic proximity Read ↗

Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.