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Article

A HAT for sleep?: epigenetic regulation of sleep by Tip60 in Drosophila.

Fly - 1 Jan 2000

Pirooznia Sheila K, Elefant Felice

Abstract excerpt

Sleep disturbances are common in neurodegenerative diseases such as Alzheimer disease (AD). Unfortunately, how AD is mechanistically linked with interference of the body's natural sleep rhythms remains unclear. Our recent findings provide insight into this question by demonstrating that sleep disruption associated with AD is driven by epigenetic changes mediated by the histone acetyltransferase (HAT) Tip60. In...

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PMID: 23572111
DOI: 10.4161/fly.24141
PMCID: PMC3732338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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