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Article

Combined fluorescent-chromogenic in situ hybridization for identification and laser microdissection of interphase chromosomes.

PloS one - 1 Jan 2013

Paz Nerea, Zabala Amaia, Royo Félix, García-Orad África, Zugaza José L, Parada Luis A

Abstract excerpt

Chromosome territories constitute the most conspicuous feature of nuclear architecture, and they exhibit non-random distribution patterns in the interphase nucleus. We observed that in cell nuclei from humans with Down Syndrome two chromosomes 21 frequently localize proximal to one another and distant from the third chromosome. To systematically investigate whether the proximally positioned chromosomes were...

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PMID: 23565206
DOI: 10.1371/journal.pone.0060238
PMCID: PMC3615066

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CISH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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