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Article

Genome organization in the human sperm nucleus studied by FISH and confocal microscopy

1 Mar 2000

Abstract excerpt

The sperm nucleus has a unique chromatin structure where the DNA is highly condensed and associated with specific proteins, the protamines. It is a nondividing cell which is also transcriptionally inactive. After fusion with an oocyte, the sperm nucleus undergoes decondensation and, in the same time, starts replication and transcription. It has been suggested that somatic chromosomes during interphase are...

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PMID: 10657050
DOI: 10.1002/(sici)1098-2795(200003)55:3<307::aid-mrd9>3.0.co;2-p

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