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Article

Regulation of skeletal muscle oxidative phenotype by classical NF-κB signalling.

Biochimica et biophysica acta - 1 Aug 2013

Remels A H V, Gosker H R, Bakker J, Guttridge D C, Schols A M W J, Langen R C J

Abstract excerpt

BACKGROUND: Impairments in skeletal muscle oxidative phenotype (OXPHEN) have been linked to the development of insulin resistance, metabolic inflexibility and progression of the metabolic syndrome and have been associated with progressive disability in diseases associated with chronic systemic inflammation. We previously showed that the inflammatory cytokine tumour necrosis factor-α (TNF-α) directly impairs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23563317
DOI: 10.1016/j.bbadis.2013.03.018

Genes

TNF
PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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