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Article

Skeletal muscle PGC-1α is required for maintaining an acute LPS-induced TNFα response.

PloS one - 1 Jan 2012

Olesen Jesper, Larsson Signe, Iversen Ninna, Yousafzai Simi, Hellsten Ylva, Pilegaard Henriette

Abstract excerpt

Many lifestyle-related diseases are associated with low-grade inflammation and peroxisome proliferator activated receptor γ coactivator (PGC)-1α has been suggested to be protective against low-grade inflammation. However, whether these anti-inflammatory properties affect acute inflammation is not...

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Source

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Identifiers

PMID: 22384185
DOI: 10.1371/journal.pone.0032222
PMCID: PMC3288087

Genes

PGC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22384185-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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