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Natural products, PGC-1 , and Duchenne muscular dystrophy

8 Jan 2020

Abstract excerpt

Peroxisome proliferator-activated receptor γ (PPARγ) is a transcriptional coactivator that binds to a diverse range of transcription factors. PPARγ coactivator 1 (PGC-1) coactivators possess an extensive range of biological effects in different tissues, and play a key part in the regulation of the oxidative metabolism, consequently modulating the production of reactive oxygen species, autophagy, and mitochondrial...

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PMID: 32528825
DOI: 10.1016/j.apsb.2020.01.001

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