Article
TLR4-Mediated Inflammatory Responses Regulate Exercise-Induced Molecular Adaptations in Mouse Skeletal Muscle.
International journal of molecular sciences - 7 Feb 2022
Fujiyoshi Haruna, Egawa Tatsuro, Kurogi Eriko, Yokokawa Takumi, Kido Kohei, Hayashi Tatsuya
Abstract excerpt
Endurance exercise induces various adaptations that yield health benefits; however, the underlying molecular mechanism has not been fully elucidated. Given that it has recently been accepted that inflammatory responses are required for a specific muscle adaptation after exercise, this study investigated whether toll-like receptor (TLR) 4, a pattern recognition receptor that induces proinflammatory cytokines, is...
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