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Article

Age-related macular degeneration and modification of systemic complement factor H production through liver transplantation.

Ophthalmology - 1 Aug 2013

Khandhadia Samir, Hakobyan Svetlana, Heng Ling Z, Gibson Jane, Adams David H, Alexander Graeme J, Gibson Jonathan M, Martin Keith R, Menon Geeta, Nash Kathryn, Sivaprasad Sobha, Ennis Sarah, Cree Angela J, Morgan B Paul, Lotery Andrew J

Abstract excerpt

PURPOSE: To investigate whether modification of liver complement factor H (CFH) production, by alteration of liver CFH Y402H genotype through liver transplantation (LT), influences the development of age-related macular degeneration (AMD). DESIGN: Multicenter, cross-sectional study. PARTICIPANTS: We recruited 223 Western European patients ≥ 55 years old who had undergone LT ≥ 5 years previously. METHODS: We...

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Identifiers

PMID: 23562165
DOI: 10.1016/j.ophtha.2013.01.004

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CFH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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