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Article

Inflammation, complement factor h, and age-related macular degeneration: the Multi-ethnic Study of Atherosclerosis.

Ophthalmology - 1 Oct 2008

Klein Ronald, Knudtson Michael D, Klein Barbara E K, Wong Tien Y, Cotch Mary Frances, Liu Kiang, Cheng Ching Y, Burke Gregory L, Saad Mohammed F, Jacobs David R, Sharrett A Richey

Abstract excerpt

OBJECTIVE: To describe the relationship of systemic inflammatory disease, complement factor H (CFH) Y402H (1277T-->C) genotype status and age-related macular degeneration (AMD) prevalence in a multiethnic population of whites, blacks, Hispanics, and Chinese. DESIGN: Population-based, cross-sectional study. PARTICIPANTS: We included 5887 persons aged 45 to 84 years with gradable AMD. METHODS: Digital fundus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18538409
DOI: 10.1016/j.ophtha.2008.03.021
PMCID: PMC2936447

Genes

CFH

Variants

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