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Article

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

Investigative ophthalmology & visual science - 1 May 2016

Hughes Anne E, Bridgett Stephen, Meng Weihua, Li Mingyao, Curcio Christine A, Stambolian Dwight, Bradley Declan T

Abstract excerpt

PURPOSE: To investigate how potentially functional genetic variants are coinherited on each of four common complement factor H (CFH) and CFH-related gene haplotypes and to measure expression of these genes in eye and liver tissues. METHODS: We sequenced the CFH region in four individuals (one homozygote for each of four common CFH region haplotypes) to identify all genetic variants. We studied associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27196323
DOI: 10.1167/iovs.15-18744
PMCID: PMC4884056

Genes

CFH
CFHR1
CFHR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.PMID 27196323Read ↗

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