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Article

Functional characterization of the human PAX3 gene regulatory region.

Genomics - 1 Apr 1999

Okladnova O, Syagailo Y V, Tranitz M, Riederer P, Stöber G, Mössner R, Lesch K P

Abstract excerpt

Spatiotemporal expression of the PAX3 gene is tightly regulated during development. We have isolated and sequenced the 5'-flanking regulatory region of human PAX3. Primer extension and ribonuclease protection mapping revealed that transcription is initiated from a single start site downstream of a TATA-like motif in human brain and peripheral tissues. Functional dissection of the gene's 5'-flanking region, which...

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Identifiers

PMID: 10191090
DOI: 10.1006/geno.1998.5711

Genes

PAX3

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