Article
Cell Cycle Regulation of the Human Polo-like Kinase (PLK) Promoter
1 Apr 1997
Abstract excerpt
Plk (polo-like kinase) is a serine-threonine kinase that appears to function in mitotic control in mammalian cells. We demonstrated previously that PLK mRNA expression is low at the G1-S transition, increases during S phase, and is maximally expressed during G2-M. In the present study, we have cloned the human PLK gene and analyzed the structure and function of 2 kilobases of its 5'-flanking region. Using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
