Article
The G1/S boundary-specific enhancer of the rat cdc2 promoter.
Molecular and cellular biology - 1 May 1995
Shimizu M, Ichikawa E, Inoue U, Nakamura T, Nakajima T, Nojima H, Okayama H, Oda K
Abstract excerpt
Multiple species of G1 cyclins and cyclin-dependent kinases are induced sequentially during G1 phase, and the expression of cyclin A and cdc2 genes is subsequently induced at the G1/S boundary. To analyze the mechanism of cdc2 promoter activation, the 5'-flanking region of the rat cdc2 gene was i...
Topics
- Animals
- Base Sequence
- CDC2 Protein Kinase
- Cell Cycle
- Cell Line
- DNA
- Enhancer Elements, Genetic
- G1 Phase
- Gene Expression Regulation
- Genes
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Rats
- S Phase