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Article

The G1/S boundary-specific enhancer of the rat cdc2 promoter.

Molecular and cellular biology - 1 May 1995

Shimizu M, Ichikawa E, Inoue U, Nakamura T, Nakajima T, Nojima H, Okayama H, Oda K

Abstract excerpt

Multiple species of G1 cyclins and cyclin-dependent kinases are induced sequentially during G1 phase, and the expression of cyclin A and cdc2 genes is subsequently induced at the G1/S boundary. To analyze the mechanism of cdc2 promoter activation, the 5'-flanking region of the rat cdc2 gene was isolated and its structural features were characterized. The highly conserved sequence between human and rat cdc2 genes...

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Identifiers

PMID: 7739568
DOI: 10.1128/MCB.15.5.2882
PMCID: PMC230519

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