Article
Identification of the functional elements in the promoter region of human DNA topoisomerase IIIbeta gene.
Biochimica et biophysica acta - 17 Sept 2004
Cho Young Hoon, Park Jee Young, Han Sang Youp, Chung In Kwon
Abstract excerpt
In this study, we have isolated and characterized the promoter region of the human DNA topoisomerase IIIbeta (hTOP3beta) gene. The 5' RACE assay showed a short exon 1 encoding only the 35-bp untranslated region and suggested the presence of multiple transcription initiation sites. The hTOP3beta gene promoter lacks a canonical TATA box or initiation element and is moderately high in GC content. Transient...
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