Article
Functional polymorphisms of interleukin-18 gene and risk of breast cancer in a Brazilian population.
Tissue antigens - 1 Aug 2014
Back L K d C, Farias T D J, da Cunha P A, Muniz Y C N, Ribeiro M C M, Fernandes B L, Fernandes C K, de Souza I R
Abstract excerpt
Interleukin-18 (IL-18) is a key cytokine responsible for immune response and involved in the process of cancer development. In this case-control study, we tested whether IL-18 promoter polymorphism contributes to breast cancer susceptibility in Brazilian patients. The two groups studied were 154 patients with breast cancer and 118 healthy individuals. The frequency of IL-18 promoter single nucleotide...
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