Article
GLTP mediated non-vesicular GM1 transport between native membranes.
PloS one - 1 Jan 2013
Lauria Ines, van Üüm Jan, Mjumjunov-Crncevic Esmina, Walrafen David, Spitta Luis, Thiele Christoph, Lang Thorsten
Abstract excerpt
Lipid transfer proteins (LTPs) are emerging as key players in lipid homeostasis by mediating non-vesicular transport steps between two membrane surfaces. Little is known about the driving force that governs the direction of transport in cells. Using the soluble LTP glycolipid transfer protein (GLTP), we examined GM1 (monosialotetrahexosyl-ganglioside) transfer to native membrane surfaces. With artificial GM1...
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