Article
Structural basis for glycosphingolipid transfer specificity.
Nature - 26 Aug 2004
Malinina Lucy, Malakhova Margarita L, Teplov Alexei, Brown Rhoderick E, Patel Dinshaw J
Abstract excerpt
Lipid transfer proteins are important in membrane vesicle biogenesis and trafficking, signal transduction and immunological presentation processes. The conserved and ubiquitous mammalian glycolipid transfer proteins (GLTPs) serve as potential regulators of cell processes mediated by glycosphingolipids, ranging from differentiation and proliferation to invasive adhesion, neurodegeneration and apoptosis. Here we...
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