Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Triple cysteine module within M-type K+ channels mediates reciprocal channel modulation by nitric oxide and reactive oxygen species.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Apr 2013

Ooi Lezanne, Gigout Sylvain, Pettinger Louisa, Gamper Nikita

Abstract excerpt

We have identified a new signaling role for nitric oxide (NO) in neurons from the trigeminal ganglia (TG). We show that in rat sensory neurons from the TG the NO donor, S-nitroso-N-acetyl-dl-penicillamine, inhibited M-current. This inhibitory effect was blocked by NO scavenging, while inhibition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthracenes
Share to Benzoates
Share to Calcitonin Gene-Related Peptide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to KCNQ Potassium Channels

Share to Nitric Oxide Donors

Share to Phenylenediamines

Share to Potassium Channel Blockers

Share to Trigeminal Ganglion

Source

Open in PubMed Open full text

Identifiers

PMID: 23554485
DOI: 10.1523/JNEUROSCI.4275-12.2013
PMCID: PMC3664272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23554485-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Triple cysteine module within M-type K+ channels mediates reciprocal channel modulation by nitric oxide and reactive oxygen species.PMID 23554485Read ↗

<i>De novo</i> nitric oxide synthesis drives tactile hypersensitivity induced by ATP-sensitive potassium channel opening in mice: Relevance to migraine and other headache disordersSemantic proximity Read ↗

A duo of redox-sensitive pore-loop cysteines controls the activity of the neural ion channel TRPM3Semantic proximity Read ↗

Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation.Semantic proximity Read ↗

Regulation of redox signalling by an electrophilic cyclic nucleotideSemantic proximity Read ↗

C-terminal dimerization activates the nociceptive transduction channel transient receptor potential vanilloid 1.Semantic proximity Read ↗

Diabetes depresses synaptic transmission in sympathetic ganglia by inactivating nAChRs through a conserved intracellular cysteine residue.Semantic proximity Read ↗

Redox signal regulation via nNOS phosphorylation at Ser847 in PC12 cells and rat cerebellar granule neurons.Semantic proximity Read ↗

Guanylyl cyclase sensitivity to nitric oxide is protected by a thiol oxidation-driven interaction with thioredoxin-1.Semantic proximity Read ↗

State-dependent and site-directed photodynamic transformation of HCN2 channel by singlet oxygen.Semantic proximity Read ↗

cGMP-dependent activation of protein kinase G precludes disulfide activation: implications for blood pressure control.Semantic proximity Read ↗

Rational design of new NO and redox sensitivity into connexin26 hemichannels.Semantic proximity Read ↗

Nitric Oxide modulates spontaneous Ca <sup>2+</sup> release and ventricular arrhythmias during β-adrenergic signalling through <i>S</i> -nitrosylation of Calcium/Calmodulin dependent kinase IISemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.