Article
TOLLIP and MUC5B modulate the effect of ambient NO2 on respiratory symptoms in infancy.
Chemosphere - 1 Sept 2024
Gorlanova Olga, Rüttimann Céline, Soti Andras, de Hoogh Kees, Vienneau Danielle, Künstle Noëmi, Da Silva Sena Carla Rebeca, Steinberg Ruth, Bovermann Xenia, Schulzke Sven, Latzin Philipp, Röösli Martin, Frey Urs, Müller Loretta
Abstract excerpt
BACKGROUND: Current knowledge suggests that the gene region containing MUC5B and TOLLIP plays a role in airway defence and airway inflammation, and hence respiratory disease. It is also known that exposure to air pollution increases susceptibility to respiratory disease. We aimed to study whether the effect of air pollutants on the immune response and respiratory symptoms in infants may be modified by...
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