Article
Mapping genes and pathways in autoimmune disease.
Trends in immunology - 1 Jul 2006
Spurkland Anne, Sollid Ludvig M
Abstract excerpt
Identifying novel genes and pathways controlling T-cell activation holds the promise of developing novel therapies for autoimmune disease and cancer. Recent advances in the human genome project have shown that it is timely for small groups searching for this Holy Grail to rethink their options. In this review, some alternative strategies employed in pursuing novel disease pathways in rodents and humans, including...
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