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Article

Efficient simulation of epistatic interactions in case-parent trios.

Human heredity - 1 Jan 2013

Li Qing, Schwender Holger, Louis Thomas A, Fallin M Daniele, Ruczinski Ingo

Abstract excerpt

Statistical approaches to evaluate interactions between single nucleotide polymorphisms (SNPs) and SNP-environment interactions are of great importance in genetic association studies, as susceptibility to complex disease might be related to the interaction of multiple SNPs and/or environmental factors. With these methods under active development, algorithms to simulate genomic data sets are needed to ensure...

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Share to Computer Simulation
Share to Epistasis, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 23548797
DOI: 10.1159/000348789
PMCID: PMC3800020

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