Article
Common and individual features of the humoral immunity dysregulation of mice homozygous at the viable motheaten (mev) mutation.
Immunology letters - 1 May 1990
Kuntz L, Fonteneau P, Loor F
Abstract excerpt
The "viable motheaten" (mev) mutation in the C57BL/6 (B6) mouse causes in mev-homozygous B6 mice a rapidly progressing and fatal autoimmune syndrome, combined with a generalized immunodeficiency. Serological analyses of a large number of mev/mev individual mice revealed profound abnormalities of the levels of various spontaneously occurring, natural antibodies and of the levels and distribution of the different...
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