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Article

Methylenetetrahydrofolate reductase C677T variant in Moroccan patients with inflammatory bowel disease.

Gene - 25 May 2013

Senhaji Nezha, Serbati Nadia, Diakité Brehima, Arazzakou Sofia, Hamzi Khalil, Badre Wafaa, Nadifi Sellama

Abstract excerpt

BACKGROUND: The association of genetic polymorphisms related to metabolism of homocysteine and folate with inflammatory bowel disease has been evidenced. Several studies have identified genetic variants of MTHFR as significant susceptibility loci for Crohn's disease (CD) and ulcerative colitis (UC). The C677T genetic polymorphism in the MTHFR gene is found to be associated with a thermolabile variant enzyme that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23542077
DOI: 10.1016/j.gene.2013.02.046

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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