Article
The methylenetetrahydrofolate reductase 1298 A>C polymorphism is associated with an increased risk of inflammatory bowel disease: evidence from a meta-analysis.
Expert review of clinical immunology - 1 Nov 2021
Yang Pingliang, Wang Li, Tang Xingming, Liang Yundan
Abstract excerpt
OBJECTIVE: The association between genetic variants in methylenetetrahydrofolate reductase (MTHFR) and risk for inflammatory bowel disease (IBD) has been widely studied. However, the results are equivocal. In this meta-analysis, we aimed to determine the association between MTHFR polymorphisms and susceptibility to IBD. METHODS: We retrieved studies from the PubMed, Web of Science, Ovid, and China National...
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