Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.

African health sciences - 1 Jun 2012

Diakite B, Tazzite A, Hamzi K, Jouhadi H, Nadifi S

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism which is involved in DNA methylation, repair, and synthesis. OBJECTIVE: We investigated if the MTHFR C677T polymorphism modulates the risk of developing breast cancer in Moroccan women. METHODS: Geno...

Topics

Adult
Alleles
Black People
Breast Neoplasms
Case-Control Studies
Confidence Intervals
Female
Folic Acid
Genetic Predisposition to Disease
Genotype
Humans
Menopause
Methylenetetrahydrofolate Reductase (NADPH2)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Morocco

Odds Ratio

Polymorphism, Restriction Fragment Length

Receptors, Progesterone

Source

Open in PubMed Open full text

Identifiers

PMID: 23056029
DOI: 10.4314/ahs.v12i2.20
PMCID: PMC3462529

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23056029-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.PMID 23056029Read ↗

Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls.Semantic proximity Read ↗

The methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Asian populations.Semantic proximity Read ↗

A meta-analysis of genotypes and haplotypes of methylenetetrahydrofolate reductase gene polymorphisms in breast cancer.Semantic proximity Read ↗

Significant association between ERCC2 and MTHR polymorphisms and breast cancer susceptibility in Moroccan population: genotype and haplotype analysis in a case-control study.Semantic proximity Read ↗

Association of the MTHFR Gene C677T Polymorphism with Breast Cancer in a Turkish Population.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene C677T polymorphism and breast cancer risk: Evidence for genetic susceptibilitySemantic proximity Read ↗

The association between methylenetetrahydrofolate reductase gene C677T polymorphisms and breast cancer risk in Chinese population.Semantic proximity Read ↗

Association Analysis of Methylenetetrahydrofolate Reductase Common Gene Polymorphisms with Breast Cancer Risk in an Iranian Population: A Case-Control Study and a Stratified Analysis.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk in Chinese population: a meta-analysis of 22 case-control studies.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis.Semantic proximity Read ↗

Interaction of MTHFR C677T and A1298C, and MTR A2756G gene polymorphisms in breast cancer risk in a population in Northeast Brazil.Semantic proximity Read ↗

Homozygosity at the C677T of the MTHFR gene is associated with increased breast cancer risk in the Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.