Article
Methylenetetrahydrofolate reductase C677T polymorphism and breast cancer risk in Moroccan women.
African health sciences - 1 Jun 2012
Diakite B, Tazzite A, Hamzi K, Jouhadi H, Nadifi S
Abstract excerpt
BACKGROUND: Methylenetetrahydrofolate (MTHFR) enzyme plays an important role in folate metabolism which is involved in DNA methylation, repair, and synthesis. OBJECTIVE: We investigated if the MTHFR C677T polymorphism modulates the risk of developing breast cancer in Moroccan women. METHODS: Genotyping was performed by PCR-RFLP method on a sample of 96 patients with breast cancer and 117 controls. RESULTS: A...
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