Article
Prevalence of methylenetetrahydrofolate reductase polymorphisms in young patients with inflammatory bowel disease.
Digestive diseases and sciences - 1 Mar 2006
Stocco Gabriele, Martelossi Stefano, Sartor Franca, Toffoli Giuseppe, Lionetti Paolo, Barabino Arrigo, Fontana Massimo, Decorti Giuliana, Bartoli Fiora, Giraldi Tullio, Ventura Alessandro
Abstract excerpt
Inflammatory bowel disease (IBD) has been related to mutations of methylenetetrahydrofolate reductase (MTHFR), a critical enzyme in the metabolism of folate and methionine, both of which are important factors in DNA methylation and synthesis. A mutated MTHFR genotype was associated with increased...
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