Article
The decapping scavenger enzyme DCS-1 controls microRNA levels in Caenorhabditis elegans.
Molecular cell - 25 Apr 2013
Bossé Gabriel D, Rüegger Stefan, Ow Maria C, Vasquez-Rifo Alejandro, Rondeau Evelyne L, Ambros Victor R, Grosshans Helge, Simard Martin J
Abstract excerpt
In metazoans, microRNAs play a critical role in the posttranscriptional regulation of genes required for cell proliferation and differentiation. MicroRNAs themselves are regulated by a multitude of mechanisms influencing their transcription and posttranscriptional maturation. However, there is only sparse knowledge on pathways regulating the mature, functional form of microRNA. Here, we uncover the implication of...
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