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Functional analysis-make or break for cancer predictability.

Mutation research - 1 Jan 2000

Deniz Miriam, Holzmann Karlheinz, Wiesmüller Lisa

Abstract excerpt

Copy number variations (CNVs) encompass a variety of genetic alterations including deletions and amplifications and cluster in regions of the human genome with intrinsic instability. Small-sized CNVs can act as initial genetic changes giving rise to larger CNVs such as acquired somatic copy number aberrations (CNAs) promoting cancer formation. Previous studies provided evidence for CNVs as an underlying cause of...

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PMID: 23541693
DOI: 10.1016/j.mrfmmm.2013.03.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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