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Article

Complex human chromosomal and genomic rearrangements.

Trends in genetics : TIG - 1 Jul 2009

Zhang Feng, Carvalho Claudia M B, Lupski James R

Abstract excerpt

Copy number variation (CNV) is a major source of genetic variation among humans. In addition to existing as benign polymorphisms, CNVs can also convey clinical phenotypes, including genomic disorders, sporadic diseases and complex human traits. CNV results from genomic rearrangements that can represent simple deletion or duplication of a genomic segment, or be more complex. Complex chromosomal rearrangements...

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Identifiers

PMID: 19560228
DOI: 10.1016/j.tig.2009.05.005
PMCID: PMC4464790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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