Article
The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling.
BMC biology - 28 Mar 2013
Khonsari Roman H, Seppala Maisa, Pradel Alan, Dutel Hugo, Clément Gaël, Lebedev Oleg, Ghafoor Sarah, Rothova Michaela, Tucker Abigael, Maisey John G, Fan Chen-Ming, Kawasaki Maiko, Ohazama Atsushi, Tafforeau Paul, Franco Brunella, Helms Jill, Haycraft Courtney J, David Albert, Janvier Philippe, Cobourne Martyn T, Sharpe Paul T
Abstract excerpt
BACKGROUND: The pituitary gland is formed by the juxtaposition of two tissues: neuroectoderm arising from the basal diencephalon, and oral epithelium, which invaginates towards the central nervous system from the roof of the mouth. The oral invagination that reaches the brain from the mouth is referred to as Rathke's pouch, with the tip forming the adenohypophysis and the stalk disappearing after the earliest...
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