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Article

Genetic Regulation of Pituitary Gland Development in Human and Mouse

1 Dec 2009

Abstract excerpt

Normal hypothalamopituitary development is closely related to that of the forebrain and is dependent upon a complex genetic cascade of transcription factors and signaling molecules that may be either intrinsic or extrinsic to the developing Rathke's pouch. These factors dictate organ commitment, cell differentiation, and cell proliferation within the anterior pituitary. Abnormalities in these processes are...

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PMID: 19837867
DOI: 10.1210/er.2009-0008

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