Article
Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids.
Developmental biology - 15 May 2011
Grevellec Armelle, Graham Anthony, Tucker Abigail S
Abstract excerpt
The parathyroid glands originate from the endoderm of the caudal pharyngeal pouches. How these parathyroids are restricted to developing in the caudal pouches is unclear. In this paper we investigate the role of Shh signalling in patterning the vertebrate pharyngeal pouches, and show that Hh signalling may be involved in restricting the expression of the parathyroid marker Gcm2 in the pharyngeal epithelium. In...
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