Article
The inductive role of Wnt-β-Catenin signaling in the formation of oral apparatus.
Developmental biology - 1 Aug 2011
Lin Congxing, Fisher Alexander V, Yin Yan, Maruyama Takamitsu, Veith G Michael, Dhandha Maulik, Huang Genkai J, Hsu Wei, Ma Liang
Abstract excerpt
Proper patterning and growth of oral structures including teeth, tongue, and palate rely on epithelial-mesenchymal interactions involving coordinated regulation of signal transduction. Understanding molecular mechanisms underpinning oral-facial development will provide novel insights into the etiology of common congenital defects such as cleft palate. In this study, we report that ablating Wnt signaling in the...
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