Article
Study of association between HLA-DR4 and DR53 and autoantibody detection in rheumatoid arthritis.
Journal of immunoassay & immunochemistry - 1 Jan 2013
Zhou Yongmei, Tan Liming, Que Qiuhua, Li Hua, Cai Lili, Cao Liping, Ye Qian, Xiong Jinwang
Abstract excerpt
The present study explored the association between human leukocyte antigen (HLA)-DR4, DR53, and auto antibodies in rheumatoid arthritis (RA) and its clinical significance. A total of 305 patients with RA and 50 healthy subjects who underwent medical examination were evaluated. HLA-DR4 and HLA-DR53 and auto antibodies were detected. The results showed that frequencies of HLA-DR4 and HLA-DR53 alleles in RA patients...
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