Article
Association of anti-cyclic citrullinated peptide antibodies and rheumatoid factor isotypes with HLA-DRB1 shared epitope alleles in Egyptian rheumatoid arthritis patients.
International journal of rheumatic diseases - 1 May 2020
Raslan Hala M, Attia Hanaa R, Hamed Ibrahim Mona, Mahmoud Hassan Eman, Salama Iman I, Ismail Sherif, Abdelmotaleb Eman, El Menyawi Manal M, Amr Khalda S
Abstract excerpt
INTRODUCTION: The most common genetic risk factor for rheumatoid arthritis (RA) is human leucocyte antigen DRB1 (HLA-DRB1) shared epitope (SE). AIM: To investigate the relationship between anti-cyclic citrullinated peptide (anti-CCP), rheumatoid factor (RF), immunoglobulin (Ig)G, IgM and IgA and HLA-DRB1 SE among Egyptian patients with RA. METHODS: Serum levels of anti-CCP antibodies and RFIgG, RFIgM, RFIgA were...
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