Article
Therapeutic approaches for shankopathies.
Developmental neurobiology - 1 Feb 2014
Wang Xiaoming, Bey Alexandra L, Chung Leeyup, Krystal Andrew D, Jiang Yong-Hui
Abstract excerpt
Despite recent advances in understanding the molecular mechanisms of autism spectrum disorders (ASD), the current treatments for these disorders are mostly focused on behavioral and educational approaches. The considerable clinical and molecular heterogeneity of ASD present a significant challenge to the development of an effective treatment targeting underlying molecular defects. Deficiency of SHANK family genes...
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