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Article

The emerging role of SHANK genes in neuropsychiatric disorders.

Developmental neurobiology - 1 Feb 2014

Guilmatre Audrey, Huguet Guillaume, Delorme Richard, Bourgeron Thomas

Abstract excerpt

The genetic heterogeneity of neuropsychiatric disorders is high, but some pathways emerged, notably synaptic functioning. A large number of mutations have been described in genes such as neuroligins, neurexins, and SHANK that play a role in the formation and the maintenance of synapses. This review focuses on the disorders associated with mutations in SHANK3 and the other members of its family, SHANK1 and SHANK2....

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Identifiers

PMID: 24124131
DOI: 10.1002/dneu.22128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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