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Article

SHANK1 and autism spectrum disorders.

Science China. Life sciences - 1 Oct 2015

Gong XiaoHong, Wang HongYan

Abstract excerpt

Autism spectrum disorders (ASD) are highly heterogeneous pediatric developmental disorders with estimated heritability more than 70%. Although the genetic factors in ASD are mainly unknown, a large number of gene mutations have been found, especially in genes involved in neurogenesis. The Neurexin-Neuroligin-Shank (NRXN-NLGN-SHANK) pathway plays a key role in the formation, maturation and maintenance of synapses,...

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Identifiers

PMID: 26335738
DOI: 10.1007/s11427-015-4892-6

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PSD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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