Article
Specific infection of central nervous system white matter by a variant of gross murine leukemia virus.
Virology - 1 Jul 1990
Simonian N A, Rosenthal L A, Korostoff J, Hickey W F, Blank K J, Gaulton G N
Abstract excerpt
Exposure of neonatal Balb.B mice to a variant of Gross murine leukemia virus, termed WB91-GV, resulted in selective white matter infection within the central nervous system. Viral antigens were detected in brain sections of animals inoculated by either intracerebral or intraperitoneal routes, but...
Topics
- AKR murine leukemia virus
- Aging
- Animals
- Animals, Newborn
- Astrocytes
- Brain
- Cells, Cultured
- Genetic Variation
- Mice
- Mice, Inbred BALB C
- Neuroglia
- Neurons
- Oligodendroglia
- Retroviridae Proteins, Oncogenic
- Viral Envelope Proteins
